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The Antimicrobial Activity of Extracts of the Lichen Hypogymnia tubulosa and Its 3-Hydroxyphysodic Acid Constituent

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The Antimicrobial Activity of Extracts of the Lichen Hypogymnia tubulosa and Its 3-Hydroxyphysodic Acid Constituent

Meral Yılmaz

a

, Turgay Tay

b

, Merih Kıvanc¸

a,*

, Hayrettin Türk

b

, and Ays¸en Özdemir Türk

a

a Anadolu University, Department of Biology, 26470 Eskis¸ehir, Turkey.

Fax: +90 2 22 3 20 49 10. E-mail: mkivanc@anadolu.edu.tr

b Anadolu University, Department of Chemistry, 26470 Eskis¸ehir, Turkey

* Author for correspondence and reprint requests

Z. Naturforsch.60 c, 35Ð38 (2005); received October 11, 2004

The antimicrobial activity and the MIC values of the diethyl ether, acetone, chloroform, petroleum ether, and ethanol extracts of the lichenHypogymnia tubulosaand its 3-hydroxy- physodic acid constituent have been investigated against some microorganisms. At least one of the extracts or 3-hydroxyphysodic acid showed antimicrobial activity againstAeromonas hydrophila,Bacillus cereus, Bacillus subtilis,Escherichia coli,Klebsiella pneumoniae,Listeria monocytogenes,Proteus vulgaris,Salmonella typhimurium,Staphylococcus aureus,Streptococ- cus faecalis, and Candida albicans. No antifungal activity of the extracts has been observed against ten filamentous fungi.

Key words: Hypogymnia tubulosa, 3-Hydroxyphysodic Acid, Antimicrobial Activity

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