Cytotoxic Hydroazulene Diterpenes from the Brown Alga Cystoseira myrica Seif-Eldin N. Ayyad

On the basis of the Beecham rule [5], the absolute con- figuration at C-4 was determined to be S by the nega- tive Cotton effect at 225 nm in the electronic circular dichroism

Comparing 1 and 4 which both possess the same acetyloxy and angeloyloxy group linked to C-21 and C-22 in 1 and vice versa in 4, the substitution pattern of compound 4 resulted in

As part of our continuing research on novel biologically active com- pounds from Chinese traditional medicine, two new clerodane diterpenes and four known compounds were isolated

a Graduate School of Natural Science and Technology, Department of Applied Bioscience and Biotechnology, Laboratory of Natural Products Chemistry, Okayama University, Tsushima

Five ingenane compounds, 1Ð5, kansuinins A and B, isolated from Euphorbia kansui, and their derivatives 7 and 9 were tested for termiticidal activity against the Japanese

The cytotoxic activity seemed to be related to inhibition of DNA synthesis, as revealed by the reduction of 5-bromo-2 ⬘ -deoxyuridine incorporation and induction of apoptosis,

Two new hydroazulenoid (prenyl guaiane) diterpenes, dictyone acetate (2) and 3,4-epoxy 13-hydroxy pachydictyol A (4) were isolated from the petroleum ether fraction of the alco-

Cytotoxicity-guided fractionation of the alcohol extract of the brown alga, Cystoseira my- rica, afforded four new cytotoxic hydroazulene diterpenes, dictyone acetate (2), dictyol