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“Expression gradient of metalloproteinases and their inhibitors from proximal to distal segments of abdominal aortic aneurysm”

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“Expression gradient of metalloproteinases and their inhibitors from proximal to distal segments of abdominal aortic aneurysm”

Journal of Applied Genetics

Aleksandra Auguściak-Duma, Karolina L. Stępień, Marta Lesiak, Ewa Gutmajster, Agnieszka Fus-Kujawa, Malwina Botor, Aleksander L. Sieroń

Corresponding author: Aleksandra Auguściak-Duma, Department of Molecular Biology, Faculty of Medical Science in Katowice, Medical University of Silesia, Katowice, Poland. E- mail: aaugusciak@sum.edu.pl (AAD). ORCID-0000-0001-5426-3277

Online Resource 3 Gene expression detected at the percentage of the analysed AAA segments

Gene Control Proximal

part

Aneurysm bag

Distal part

n= 7 13 13 20

ADAMTS1 100 100 100 100

ADAMTS8 100 77 77 60

ADAMTS13 57 38 31 30

MMP1 100 77 85 90

MMP2 100 100 100 100

MMP3 71 62 77 65

MMP7 100 77 77 80

MMP8 100 100 100 100

MMP9 100 100 92 95

MMP10 29 0 15 20

MMP11 100 100 100 100

MMP12 100 100 77 100

MMP13 86 62 77 75

MT1-MMP 100 100 100 100

MT2-MMP 71 69 46 60

MT3-MMP 100 92 100 85

TIMP1 100 100 100 100

TIMP2 100 100 100 100

TIMP3 100 100 100 100

TIMP4 86 77 92 80

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