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Supplementary Figure 2 – Survival analysis for the 542 subjects that had a retinopathy diagnosis develop during the period of follow up

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Supplementary Figure 2 – Survival analysis for the 542 subjects that had a retinopathy diagnosis develop during the period of follow up

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Supplementary Table S1 - Incidence rates by standard deviation quartile band and mean HbA1c quartile bands Mean HbA1c quartile

(mmol/mol) SD quartile No retinopathy N (%) Retinopathy N (%) Total (N)

<48

<3.2 284 (86.3) 45 (13.7) 329

3.2 – 5.2 150 (84.8) 27 (15.3) 177

5.3 – 9.1 55 (87.3) 8 (12.7) 63

>9.1 12 (92.3) 1 (7.7) 13

48 – 54

<3.2 183 (84.7) 33 (15.3) 216

3.2 – 5.2 212 (84.5) 39 (15.5) 251

5.3 – 9.1 128 (76.7) 39 (23.4) 167

>9.1 59 (81.9) 13 (18.1) 72

55 – 63

<3.2 48 (78.7) 13 (21.3) 61

3.2 – 5.2 117 (79.1) 31 (21.0) 148

5.3 – 9.1 181(77.4) 53 (22.7) 234

>9.1 131 (75.7) 42 (24.3) 173

>63

<3.2 11 (91.7) 1 (8.3) 12

3.2 – 5.2 36 (66.7) 18 (33.3) 54

5.3 – 9.1 101 (60.8) 65 (39.2) 166

>9.1 261 (69.6) 114 (30.4) 375

SD – standard deviation

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