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Verbenacine and Salvinine: Two New Diterpenes from Salvia verbenaca Bahar Ahmed

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Verbenacine and Salvinine: Two New Diterpenes from Salvia verbenaca

Bahar Ahmed

a,*

, Tawfeq A. Al-Howiriny

b

, Adnan J. Al-Rehaily

b

, and Jaber S. Mossa

b

a Medicinal, Aromatic and Poisonous Plants Research Center

b Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia. Fax: +(9 66)-1-4 67-72 45. E-mail: bahmed@ksu.edu.sa

* Author for correspondence and reprint requests

Z. Naturforsch.59 c, 9Ð14 (2004); received March 10/May 28, 2003

Two new diterpenes namely verbenacine (1) and salvinine (2) have been isolated from the aerial parts ofSalvia verbenaca.Their structures have been elucidated on the basis of chemi- cal and spectral data as 3α-hydroxy-19-carboxykaur-15-ene and 19-hydroxy-12,14-dioxo labda-15,17-diene.

Key words: Salvia verbenaca, Verbenacine, Salvinine

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