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Multivariate analysis in CN cohort

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Multivariate analysis in CN cohort 　 Multivariate analysis in CN cohort 　

Variables HR (95% CI) p-value Variables HR (95% CI) p-value

Patient initial status

Recurred vs. Denovo 2.08 (0.81-5.39) 0.13 Patient initial status

Recurred vs. Denovo 2.22 (0.86-5.73) 0.1 ESR1

Altered vs Wild type 2.40 (1.04-5.54) 0.04 PTEN

Loss vs Wild type 3.50 (1.04-11.82) 0.04

Multivariate analysis in US cohort 　 Multivariate analysis in US cohort 　

Variables HR (95% CI) p-value Variables HR (95% CI) p-value

Patient initial status

Recurred vs. Denovo 6.10 (0.71-52.68) 0.1 Patient initial status

Recurred vs. Denovo 6.13 (0.71-52.75) 0.1 ESR1

Altered vs Wild type 1.20 (0.25-5.81) 0.82 PTEN

Loss vs Wild type 1.28 (0.16-10.27) 0.82 HR, hazards ratio; CI, confidence interval

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