• Keine Ergebnisse gefunden

Correction to: Expression of CD44 variant 9 induces chemoresistance of gastric cancer by controlling intracellular reactive oxygen spices accumulation

N/A
N/A
Protected

Academic year: 2022

Aktie "Correction to: Expression of CD44 variant 9 induces chemoresistance of gastric cancer by controlling intracellular reactive oxygen spices accumulation"

Copied!
2
0
0

Wird geladen.... (Jetzt Volltext ansehen)

Volltext

(1)

Vol:.(1234567890)

Gastric Cancer (2021) 24:1100–1101 https://doi.org/10.1007/s10120-021-01205-5

1 3

CORRECTION

Correction to: Expression of CD44 variant 9 induces chemoresistance of gastric cancer by controlling intracellular reactive oxygen spices accumulation

Tomoko Jogo

1,2

 · Eiji Oki

1

 · Ryota Nakanishi

1

 · Koji Ando

1

 · Yuichiro Nakashima

3

 · Yasue Kimura

1

 · Hiroshi Saeki

4

 · Yoshinao Oda

2

 · Yoshihiko Maehara

5

 · Masaki Mori

1

Published online: 5 July 2021

© The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2021

Correction to: Gastric Cancer

https:// doi. org/ 10. 1007/ s10120- 021- 01194-5

In the original publication of the article, the Figure 1 and Table 1 were published with errors. The corrected Fig.  1 and Table 1 is given in this correction.

Publisher’s Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The original article can be found online at https:// doi. org/ 10. 1007/

s10120- 021- 01194-5.

* Eiji Oki

okieiji@surg2.med.kyushu-u.ac.jp

1 Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

2 Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

3 Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan

4 Department of General Surgical Science, Graduate School of Medicine, Gunma University, Gunma, Japan

5 Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, Japan

(2)

1101 Correction to: Expression of CD44 variant 9 induces chemoresistance of gastric cancer by…

1 3

Fig. 1 Flowchart depicting the patient selection process. This study included 596 primary GC patients who underwent surgery between January 2006 and December 2016. Among these patients, 193 GC patients were treated without preopera- tive chemotherapy from 2008 to 2012 and 29 GC patients received preoperative chemo- therapy from 2006 to 2016.

Among the 69 GC patients with pathological stage II–III without preoperative chemotherapy, 36 patients completed postop- erative adjuvant chemotherapy, 12 patients were treated with noncompleted postoperative adjuvant chemotherapy, and 21 patients did not receive postop- erative adjuvant chemotherapy.

GC gastric cancer, CD44v9 CD44 variant 9

Table 1 Association between CD44v9 expression in resected specimens and clinicopathological factors in GC patients who underwent surgery without preoperative therapy

Bold value indicates a significant difference

CD44v9 CD44 variant 9, GC gastric cancer, pStage pathological stage, GPx2 glutathione peroxidase 2

Factors CD44v9-negative

n = 142 (%) CD44v9-positive

n = 51 (%) p-value

Age (average ± SD) 64.2 ± 12.1 66 ± 11.5 0.3659

Sex Male 87 (61.3) 41 (80.4) 0.0154

Female 55 (38.7) 10 (19.6)

Differentiation Well/Moderately 67 (47.2) 27 (52.9) 0.5163

Poorly/Signet-ring cells 75 (52.8) 24 (47.1)

Depth of tumor invasion T1/2 103 (72.5) 26 (51.0) 0.0088

T3/4 39 (27.5) 25 (49.0)

Lymphatic permeation Absent 99 (69.7) 22 (43.1) 0.0012

Present 43 (30.3) 29 (56.9)

Vascular invasion Absent 117 (82.4) 35 (68.6) 0.0470

Present 25 (17.6) 16 (31.4)

Lymph node metastasis Absent 93 (65.5) 27 (53.0) 0.1309

Present 49 (34.5) 24 (47.0)

Distant metastasis Absent 139 (97.9) 45 (88.2) 0.0114

Present 3 (2.1) 6 (11.8)

pStage I/II 113 (79.6) 34 (66.7) 0.0839

III/IV 29 (20.4) 17 (33.3)

GPx2 expression Negative 85 (59.9) 12 (23.5) < 0.0001

Positive 57 (40.1) 39 (76.5)

Referenzen

ÄHNLICHE DOKUMENTE

Zeidan AM, Podoltsev NA, Wang X et al (2019) Temporal patterns and predictors of receiving no active treatment among older patients with acute myeloid leukemia in the United States:

In late 2020, we observed that oxygenation could be improved in some patients by applying a mask (e.g. a nebulisation mask or simple oxygen mask) to ongoing HFNC.. This procedure

As a result of the high antitumour activity and toxicity profile reported with P and DOX [12-14, 18-21] with 20% congestive heart failure (CHF) after cumulative doses of DOX &gt;

A total of 56 patients undergoing neoadjuvant chemo- therapy and representing the placebo arm of the Gepar- Nuevo trial underwent immune monitoring on blood samples collected at

The goal of our study presented here was to examine the predictive value of MAPT, TOPO IIa, and HER-2 mRNA expression in breast cancer patients who received neoadjuvant

Tumor samples were classified accord- ing to four prognostic and two predictive previ- ously described gene signatures and compared with standard parameters as histologic subtype,

7 Cholesterol Metabolism and Therapeutic Innovations, Cancer Research Center of Toulouse (CRCT), UMR 1037, INSERM, UPS, Université de Toulouse, CNRS, 31037 Toulouse,

Patients with a history of hospitalization during adjuvant chemotherapy had a worse overall survival compared to patients who were not hospitalized (P &lt; 0.001).. Conclusion