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PD-0yr (untreated Parkinson’s disease patients), PD-1yr (patients treated for one year), PD-2yr (patients treated for two years)

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Supplementary Table 4. Changes in immune cell populations associated with age.

Control PD-0yr PD-1yr PD-2yr

P r P r P r P r

Effector CD4 T cells

CD4+CD25−CD127- 0.295 0.253 0.810 0.046 0.004** 0.599 0.578 −0.201 Naive/central memory

CD4 T cells

CD4+CD25−CD127+ 0.184 0.253 0.703 −0.072 0.039* −0.453 0.210 0.434 Plasma cells

CD19−CD138+CD38+ 0.071 −0.411 0.012* 0.461 0.754 −0.075 0.957 −0.019 Correlation between age and cell population levels. PD-0yr (untreated Parkinson’s disease patients), PD-1yr (patients treated for one year), PD-2yr (patients treated for two years). P < 0.05 (*); P < 0.005 (**).

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