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Figure S1: Doxycycline causes mitonuclear protein imbalance in glioma cells under low glucose conditions. LNT-229, G55 and U343 glioma cells were incubated in serum containing (10% FCS) or serum-free (No FCS) medium with glucose restriction (2 mM glucose) with vehicle, 0.1 or 10 µg/ml doxycycline under normoxic conditions for 24 h as indicated. Cellular lysates were analyzed by immunoblot with antibodies for MT-CO1, SDHA and actin.
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[1] Lole KS, Bollinger RC, Paranjape RS, Gadkari D, Kulkarni SS, Novak NG, Ingersoll R, Sheppard HW, Ray SC (1999) Full-length human immunodeficiency virus type 1 genomes from
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