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Chemical Constituents from the Leaves of Aglaia odorata Dong-Xiao Wang

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Chemical Constituents from the Leaves of Aglaia odorata

Dong-Xiao Wanga and Shu-Min Yangb,*

a Department of Pharmaceutical Care, General Hospital of Chinese PLA, Beijing, 100853, P. R. China

b School of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing, 100069, P. R. China. Fax: +86 01 83911533. E-mail: smyang@ccmu.edu.cn

* Author for correspondence and reprint requests

Z. Naturforsch. 68 c, 82 − 86 (2013); received March 26/October 19, 2012

A new dammarane triterpene, 3-acetoxy aglinin C (1), and a new aglain, 10-oxo-aglaxif- lorin D (2), along with fi ve known compounds, 37, were isolated from the leaves of Aglaia odorata using chromatographic methods. The structures of 1 and 2 were determined on the basis of spectroscopic analyses. Bioactivities of 17 against AGZY 83-a (human lung cancer cell line) and SMMC-7721 (human liver cancer cell line) cells were determined.

Key words: Aglaia odorata, 3-Acetoxy Aglinin C, 10-Oxo-aglaxifl orin D

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