Sesquiterpene Lactones from Achillea chrysocoma and Achillea coarctata Milka Todorova and Elena Tsankova*

a Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, BulgariaZ.

The detailed investigation of a methanolic extract of aerial parts of Achillea nobilis resulted in the isolation of

From dichloromethane extracts of flowerheads of Achillea pannonica Scheele three ses- quiterpenes were isolated and identified: 11,13-dehydrodesacetylmatricarin,

From dichloromethane extracts of flowerheads of Achillea pannonica Scheele three ses- quiterpenes were isolated and identified: 11,13-dehydrodesacetylmatricarin,

b Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria.. c Institute of Microbiology, Bulgarian Academy of Sciences,

Since this plant is used against malaria and other diseases in the Guatemalan folk medicine, the main sesquiterpene lactones were tested for their activities against

Since sesquiter- pene lactones have been found to be active against Plasmodium parasites (Franc¸ois et al., 1996; Woer- denbag et al., 1994), we continued our pharmaco- logical

a Institute of Organic Chemistrywith Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria..